Modern Healthspan: How a Simple Daily Multivitamin Slows Your Biological Clock

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Peer-Reviewed Research
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Modern Healthspan

Video Summary · April 15, 2026

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Key Takeaways

  • Take a daily multivitamin (like Centrum Silver) – the COSMOS trial showed it slowed biological aging in older adults when taken for 2+ years
  • Prioritize multivitamins over cocoa extract – while both were tested, only multivitamins showed significant epigenetic age-slowing effects
  • Start earlier if you have accelerated aging – benefits were more pronounced in participants with existing health risks or faster biological aging
  • Track with epigenetic clocks – GrimAge and PhenoAge were most responsive to multivitamin intervention in the study

Supplements & Protocols Mentioned

  • Centrum Silver multivitamin – exact dosage not specified, but taken daily
  • Cocoa extract supplement – tested but showed minimal effects on epigenetic aging

Notable Quotes

“We found that multivitamins delayed the increase in the second generation of clocks, the GrimAge and the PhenoAge” – Dr. Sidong Li

“The findings were much stronger and more compelling for the multivitamin intervention relative to the cocoa extract intervention” – Dr. Howard Sesso

Bottom Line

Take a daily multivitamin (like Centrum Silver) for at least 2 years to measurably slow biological aging, especially if you have existing health risks or accelerated aging markers.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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