Evidence-based longevity and healthspan research
M Max Lugavere Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Identify your strengths and align them with activities that bring you joy and fulfillment. Set meaningful goals that contribute to a larger purpose, rather than fleeting achievements. Cultivate relationships that support and inspire you to grow in alignment with your…
B Brad Stanfield Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Retatrutide, a triple hormone receptor agonist targeting GLP-1, GIP, and glucagon, produces unprecedented weight loss, averaging 24.2% of body weight at 48 weeks. Patients on retatrutide experienced up to 20.9% incidence of dysesthesia (abnormal skin sensations) at the highest dose,…
R Rhonda Patrick Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Always check for NSF certification when purchasing creatine or any supplement to avoid harmful contaminants like lead. Look for the NSF certified sports logo on product packaging or websites when buying supplements. Products & Gear Mentioned NSF certified sports logo…
B Brad Stanfield Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Retatrutide (triple-hormone agonist) achieved unprecedented weight loss (24-29% body weight) by activating GLP-1, GIP, and glucagon pathways. Monitor for dysesthesia (abnormal skin sensations) – 1 in 5 patients on the highest dose reported this novel side effect. Prioritize resistance training…
B Bryan Johnson Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Avoid ultra-processed foods that are high in fats, sugar, and salt, as they are designed to trigger addiction and harm health. Focus on whole, nutrient-dense ingredients like lentils, shiitake mushrooms, broccoli, cauliflower, macadamia nuts, hemp seeds, flax seeds, and walnuts….
G Gabrielle Lyon Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Shift focus from weight loss to strength training if traditional dieting isn’t working – building physical capability boosts confidence more than restrictive eating Consider GLP-1 medications if struggling with persistent weight issues, as they’re currently the most effective FDA-approved option…
S Siim Land Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Morning bowel movement within a few hours of waking signals a healthy circadian rhythm. Align digestion with circadian rhythm by waking, eating, and sleeping at consistent times daily. Morning daylight exposure helps synchronize your body clock and digestion. Notable Quotes…
R Rhonda Patrick Video Summary · April 7, 2026 View Full Protocol → Key Takeaways Avoid storing spicy or acidic foods in plastic containers – Chemicals like BPA leach faster when exposed to heat or acidity. Choose glass or metal containers for hot sauces and other acidic foods to minimize chemical exposure. Occasional use is…
D Dr. Karan Video Summary · April 7, 2026 View Full Protocol → Key Takeaways Aim for 10g of fiber per meal to support gut health and cholesterol management (based on Dr. Karan’s personal success story). Prioritize fiber-rich foods daily to improve microbiome health, mood, skin, and reduce long-term disease risks. Don’t compromise gut health…
C Conquer Aging Video Summary · April 21, 2026 View Full Protocol → Key Takeaways Focus on T-cell health – They drive immune memory, persist for decades, and their dysfunction accelerates aging through inflammation. Monitor immune surveillance decline – Poor T-cell function leads to accumulation of senescent cells and higher cancer risk. Address thymus health…
M Modern Healthspan Video Summary · April 7, 2026 View Full Protocol → Key Takeaways Mitopure (urolithin A) is being clinically tested for brain health, with trials underway to confirm blood-brain barrier penetration. Prioritize mitophagy activators to clear damaged mitochondria – shown to improve muscle, immune function, and potentially neurodegeneration. Watch for upcoming results from…
R Rhonda Patrick Video Summary · April 7, 2026 View Full Protocol → Key Takeaways Avoid black plastic containers – They contain recycled electronics with flame retardants that leach into food. Never heat food in plastic – Heat and acidic foods (like spicy sauces) accelerate chemical leaching (BPA, phthalates). Use glass/Pyrex for storage – Especially…
