Michael Greger: The Best Source and Dose of Plant Sterols for Lowering Cholesterol

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Peer-Reviewed Research
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Michael Greger

Video Summary · March 4, 2026

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Key Takeaways

  • Take 2-3 grams of phytosterols daily for LDL reduction, ideally with meals for maximum absorption.
  • Use esterified phytosterol supplements (not bulk powder) – they’re more effective than free sterols.
  • Test LDL before and after 1 month to confirm individual response (some see no effect or even increased LDL).
  • Avoid phytosterol-fortified margarines – opt for supplements or verified fortified foods (rare).

Supplements & Protocols Mentioned

  • Phytosterol supplements: 2-3g/day, taken with meals. Look for USP-verified brands or Consumers Lab-approved options.
  • Esterified phytosterols (capsules) outperform free sterols (powder) for LDL lowering.

Notable Quotes

“Adding 2 grams of phytosterols a day to your routine may be equivalent to like quadrupling your statin dose.”

Bottom Line

Try 2-3g/day of esterified phytosterol supplements with meals, then verify LDL reduction with testing. Skip powders and margarines.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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