Siim Land: One Blood Marker That Predicts Stroke (Most People Never Test It)

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Peer-Reviewed Research
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Siim Land

Video Summary · April 1, 2026

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Key Takeaways

  • **Test homocysteine levels** regularly, especially if you’re young or have no traditional risk factors for stroke or cardiovascular disease.
  • **Aim for homocysteine levels** below 10 micromoles per liter, ideally closer to 5 micromoles per liter for optimal health.
  • **Supplement with B vitamins (B9, B12, B6)** if homocysteine is high and B vitamin levels are low.
  • **Consider glycine, serine, and trimethylglycine (TMG)** to help lower homocysteine levels.
  • **Avoid excessive endurance exercise**, as it can temporarily raise homocysteine levels.

Supplements & Protocols Mentioned

  • **B9 (folate)**, **B12**, and **B6** supplementation can lower homocysteine by approximately 4 micromoles per liter.
  • **Trimethylglycine (TMG)**: Up to 4 grams daily for six weeks to lower homocysteine by 1.23 micromoles per liter.
  • **Glycine** and **serine** supplementation can also help reduce homocysteine levels.

Products & Gear Mentioned

  • **Bon Charge infrared sauna blankets**: Use for 20-minute sessions to improve cardiovascular health and lower heart disease risk.

Notable Quotes

“Homocysteine is an early warning sign. It’s decades early, but it’s important to listen to it.”

Bottom Line

Regularly monitor and actively manage your homocysteine levels through testing, supplementation, and healthy lifestyle choices to reduce long-term risk of stroke and cardiovascular disease.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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