Rhonda Patrick: If You Take Supplements, You Need to See This

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Peer-Reviewed Research
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Rhonda Patrick

Video Summary · April 24, 2026

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Key Takeaways

  • Curcumin lowers TNF alpha, a major inflammatory cytokine linked to aging. Phytosomal curcumin enhances bioavailability.
  • Urolithin A activates mitophagy, clearing damaged mitochondria and rejuvenating cells, which can improve muscle strength and immune function.
  • Glutamine supports immune health, especially in endurance athletes, by reducing respiratory illnesses.

Supplements & Protocols Mentioned

  • Phytosomal Curcumin: Improves bioavailability and lowers TNF alpha.
  • Urolithin A: 1,000 mg/day shown to boost immune function, VO2 max, and muscle strength in studies.
  • Glutamine: Supports immune health, particularly in endurance athletes.

Notable Quotes

“Curcumin is one of the most naturally occurring dietary compounds that lowers TNF alpha.”

“Urolithin A induces mitophagy, rejuvenating mitochondria and improving energy utilization.”

Bottom Line

Consider adding phytosomal curcumin and urolithin A to your supplement regimen to reduce inflammation, clear damaged mitochondria, and support immune function. Glutamine is beneficial for athletes prone to respiratory illnesses.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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