Evidence-based longevity and healthspan research
S Siim Land Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Rapamycin showed potential in preclinical models (worms, flies, mice) for lifespan extension (20-25%) and improved muscle performance. In a human trial, Rapamycin dosed once a week did not outperform placebo in improving muscle performance in older adults aged 65-85. Focus…
M Modern Healthspan Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Optimize ketone levels – The brain can use ketones as an alternative fuel source when glucose metabolism is impaired. Intermittent fasting – Helps shift the brain into ketone-burning mode by depleting glycogen stores. Reduce processed carbs – Minimize foods that…
M Max Lugavere Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Identify environments where you feel safe and comfortable to help regulate bowel movements. Be mindful of how certain settings, like department stores, may trigger the urge to poop. Address stress as it can lead to diarrhea and disrupt normal bowel…
R Rhonda Patrick Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Vitamin D: Supplement with Vitamin D daily to support immune function, especially during winter months. Zinc: Take Zinc supplements at the first sign of illness to reduce the duration and severity of colds. Probiotics: Incorporate a high-quality probiotic supplement to…
M Max Lugavere Video Summary · April 25, 2026 View Full Protocol → Key Takeaways Prototype quickly to learn faster through experience, not perfection. Immerse yourself in unfamiliar areas (e.g., podcasts, industry visits) to gain firsthand insights. Iterate rapidly to uncover what you truly enjoy or want to pursue. Notable Quotes “So fail faster to…
M Max Lugavere Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Normalize farting – Everyone farts 10-20 times per day, which is completely normal. Track your frequency if concerned – Log your daily farts to confirm you’re within the healthy range. Don’t shame others for farting – It’s a natural bodily…
M Mark Hyman Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Track your biology regularly using blood tests and MRIs to stay proactive about your health. Focus on individualized health data rather than relying solely on general population averages. Use tools to monitor your health metrics and understand your current health…
B Ben Greenfield Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Sleep deprivation – Staying up all night accelerates aging Smoking – Significantly increases pace of aging Chronic stress – Maintain high stress levels to age faster Overeating – Excess calories speed up biological aging Social isolation – Weak relationships age…
M Max Lugavere Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Avoid comparing potential partners to social media highlight reels, as it creates unrealistic expectations. Focus on building trust rather than immediately looking for red flags in early dating stages. Lower unrealistic expectations set by social media to foster healthier relationships….
D Diary of a CEO Video Summary · April 24, 2026 Key Takeaways Measure your waist circumference – Men should stay below 40 inches, women below 35 inches to avoid dangerous visceral fat levels. Get a DEXA scan if possible – The most accurate way to measure visceral fat (ideal is under 300g). Break the…
M Mark Hyman Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Get advanced testing if standard labs show “normal” results but you still feel unwell (e.g., cardiovascular biomarkers). Eliminate processed foods – Kim shifted to whole foods and grew her own kitchen garden. Rebound exercise – Kim used a mini trampoline…
R Rhonda Patrick Video Summary · April 24, 2026 View Full Protocol → Key Takeaways Curcumin lowers TNF alpha, a major inflammatory cytokine linked to aging. Phytosomal curcumin enhances bioavailability. Urolithin A activates mitophagy, clearing damaged mitochondria and rejuvenating cells, which can improve muscle strength and immune function. Glutamine supports immune health, especially in endurance…
