Michael Greger: Why I Don’t Recommend Policosanol Cholesterol-Lowering Supplements

Key Takeaways

• Policosanol supplements show inconsistent LDL-lowering effects—independent studies failed to replicate early impressive results.
• Phytosterols (2g/day) and red yeast rice remain evidence-backed options for cholesterol management (see Greger’s other videos).
• Avoid policosanol—prior positive studies were industry-funded; real-world efficacy matches placebo.

Supplements & Protocols Mentioned

• Policosanol: 2mg–80mg doses tested (ineffective vs. placebo).
• Phytosterols: 2g/day dose recommended in Greger’s other videos.
• Red yeast rice: Mentioned as effective (but cautioned in upcoming video).

Notable Quotes

“The bottom line is that policosanols lost their luster as cholesterol lowering agents.”

Bottom Line

Skip policosanol—opt for phytosterols (2g/day) or red yeast rice (with caution) for cholesterol support, and prioritize dietary changes first.

Watch the Full Video