Rhonda Patrick: The best supplement for boosting NAD
Peer-Reviewed Research
Key Takeaways
- NR (Nicotinamide Riboside) is the most effective NAD booster because larger molecules like NMN or NAD itself can’t efficiently enter cells due to phosphate groups.
- Avoid untested NMN supplements – 17 out of 20 products tested didn’t contain actual NMN or failed label claims.
- Even if you take NMN, your body converts it back to NR before cellular absorption – so NR is the more direct and tested option.
Supplements & Protocols Mentioned
- Nicotinamide Riboside (NR) – The most safety-tested NAD precursor supplement.
- Nicotinamide Mononucleotide (NMN) – Requires conversion to NR for cellular uptake; many products are mislabeled.
Notable Quotes
“NR is the biggest piece of NAD that can get into a cell”
“NMN has to be degraded down to NR in order to get into cells”
Bottom Line
Choose nicotinamide riboside (NR) over NMN for NAD boosting – it’s more reliably absorbed and better tested. Verify any NMN product’s purity through third-party testing if using.
Explore supplements mentioned in this video
Explore More
- Rhonda Patrick’s Full Protocol — supplements, dosages, and daily routine
- Compare All Protocols — side-by-side protocols
Watch the Full Video
Medical Disclaimer
This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.
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