Rhonda Patrick: 2 Supplements Everyone Over 65 Should Be Taking (For Brain Health & Longevity)

ByLongevity Notes Editorial
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Peer-Reviewed Research
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Rhonda Patrick

Video Summary · February 27, 2026

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Key Takeaways

  • Take a multivitamin daily if you’re 65 or older to reduce brain aging by 2 years and reverse episodic memory decline by 5 years.
  • Supplement with omega-3s (fish oil or microalgae) at 1.5-2 grams daily for brain health.
  • Take magnesium daily, ranging from 150-400 mg depending on activity level and lifestyle.
  • Use vitamin D3 supplements at 4,000 IU daily to reach optimal levels (40-60 nanograms per milliliter).

Supplements & Protocols Mentioned

  • Multivitamin: Standard, affordable option like Centrum Silver.
  • Omega-3s: 1.5-2 grams daily from fish oil or microalgae.
  • Magnesium: 150-400 mg daily.
  • Vitamin D3: 4,000 IU daily to reach 40-60 nanograms per milliliter.

Bottom Line

If you’re over 65, start taking a multivitamin, omega-3s, magnesium, and vitamin D3 daily to significantly improve brain health and slow cognitive aging.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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