Michael Greger: Podcast: Everything You Wanted to Know About B12 (Part 2)

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Peer-Reviewed Research
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Michael Greger

Video Summary · May 14, 2026

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Key Takeaways

  • Get 4-7 mcg of B12 daily for optimal function (higher than the RDA of 2.4 mcg).
  • Take 50 mcg daily or 2,000 mcg weekly – both protocols work equally well for maintaining B12 levels.
  • For food sources: Consume B12-fortified foods 3x/day (e.g., 2 mcg per meal via fortified soy milk or nutritional yeast).
  • Take high-dose supplements on an empty stomach to boost absorption by 60%.
  • Don’t worry about B12 overdose – excess is excreted and high supplement doses show no mortality risk.

Supplements & Protocols Mentioned

  • 50 mcg daily chewable B12 tablets
  • 2,000 mcg weekly B12 dose
  • 75 mcg per serving in Leafside meals (fortified option)

Notable Quotes

“High intake of vitamin B12 in the form of supplements was not associated with any adverse effect on mortality and therefore can be regarded as safe.”

Bottom Line

Choose either daily 50 mcg B12 supplements or weekly 2,000 mcg doses, or get sufficient B12 through 3 daily servings of fortified foods – all options effectively maintain healthy levels without safety concerns.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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