Rhonda Patrick: Does caffeine negate creatine’s benefits?

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Rhonda Patrick

Video Summary · March 30, 2026

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Key Takeaways

  • Mix creatine with coffee or teaRhonda Patrick combines her creatine with morning coffee without concern about caffeine interference.
  • Take 10g creatine daily – Split into two 5g doses (though Rhonda takes both doses in the morning for cognitive benefits).
  • Only avoid caffeine with creatine if consuming extremely high doses (e.g., caffeine pills), not normal coffee/tea intake.

Supplements & Protocols Mentioned

  • Creatine – 10g daily (split into 5g doses, taken with morning coffee/tea).

Notable Quotes

“Don’t be worried about coffee negating the effects [of creatine] unless you’re consuming massive, massive amounts of caffeine.”

Bottom Line

Mix creatine with your morning coffee or tea – caffeine won’t interfere unless taken in extreme doses. Take 10g daily (split into two 5g servings if preferred).

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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