Rhonda Patrick: The 8 Supplements I’d Take to a Desert Island

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Peer-Reviewed Research
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Rhonda Patrick

Video Summary · April 29, 2026

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Key Takeaways

  • Take 4,000 IU vitamin D daily – Critical for immune function and synergizes with omega-3s to slow biological aging.
  • Consume 1.6-2g marine omega-3s daily – Raises omega-3 index to 8%+, linked to 5-year lifespan increase and 50% lower Alzheimer’s risk.
  • Use magnesium glycinate – Supports sleep and muscle function (dosage not specified).
  • Take 10g creatine daily – Enhances brain and muscle performance beyond typical 5g athletic doses.
  • Prioritize sulforaphane (Avmacol/Nutramax) – Potent activator of cellular detox pathways.

Supplements & Protocols Mentioned

  • Vitamin D: 4,000 IU/day
  • Marine omega-3s: 1.6-2g/day (EPA/DHA)
  • Multivitamin: Unspecified brand/dose
  • Magnesium glycinate: Preferred form (dose unspecified)
  • Sulforaphane: From Avmacol or Nutramax
  • Creatine: 10g/day
  • Ubiquinol: Form of CoQ10 (dose unspecified)
  • Phytosomal curcumin: Enhanced absorption form (dose unspecified)

Notable Quotes

“Low omega-3 index was like smoking in terms of life expectancy.”

“People with a high omega-3 index that do not smoke have the longest life expectancy.”

Bottom Line

Prioritize vitamin D (4,000 IU) and marine omega-3s (2g/day) as foundational supplements, combined with exercise for maximum longevity benefits.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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