Products mentioned
Every supplement referenced across the protocol pages, in one place. This is not a “best of” list and it is not a recommendation — several items here sit behind weak evidence, and the notes say so. Where a protocol page exists, read it before you buy anything.
The list
Creatine monohydrate
The most consistently supported supplement on this site. · read the evidence
Omega-3 (EPA & DHA)
Cardiovascular and triglyceride evidence is the strongest part of the case. · read the evidence
Vitamin D3
Worth correcting a measured deficiency; less clear as a blanket supplement. · read the evidence
Vitamin K2
Usually discussed alongside D3 for calcium handling.
Magnesium
Common dietary shortfall; sleep and blood-pressure signals are modest. · read the evidence
Collagen peptides
Skin and joint endpoints; not a longevity intervention. · read the evidence
Glycine
Appears in several expert stacks, usually paired with NAC.
L-theanine
Calm-alertness; best-studied with caffeine.
Melatonin
Circadian timing rather than sedation; low doses.
Curcumin
Absorption is the whole ballgame; look for a bioavailable form.
CoQ10
Mostly discussed for statin users and heart failure.
Quercetin
Senolytic interest is animal-stage — the senolytics page is graded D. · read the evidence
Berberine
Glucose handling; often over-sold as “natural metformin”. · read the evidence
Ashwagandha
Stress and sleep endpoints; watch liver-safety case reports.
Zinc
Correct a deficiency; chronic high doses displace copper.
Lutein & zeaxanthin
Macular pigment and visual function.
Cocoa flavanols
Blood-pressure and endothelial signal from COSMOS.
Extra-virgin olive oil
The one “supplement” that is really just food.
Multivitamin
Insurance, not an intervention; COSMOS-Mind is the interesting one.
How to use this page. Start from the
protocol index, read the grade, and only then come back here. Buying a supplement with a D-grade evidence base is a choice, not a protocol.
Affiliate disclosure. The iHerb and Amazon links on this page are affiliate links: if you buy through them, Longevity Notes earns a small commission at no extra cost to you. It costs you nothing and it does not change what we write — evidence grades are assigned before any product is linked, and several items above are linked precisely so you can see how weak their evidence is. Longevity Notes is a participant in the Amazon Services LLC Associates Program. Nothing on this page is medical advice.