Protocols
Every protocol breakdown on Longevity Notes — 31 pages, grouped by type. Each one reads the human trials and says plainly what holds up and what does not.
People — expert protocol stacks
- Andrew HubermanGrade C
- Peter AttiaGrade C
- David SinclairGrade C
- Bryan Johnson — BlueprintGrade C
- Dr. Brad StanfieldGrade B
- Dr. Matt Kaeberlein — OptispanGrade B
- Dr. Gabrielle Lyon — muscle-centricGrade B
- Dr. Rhonda PatrickGrade C
- Dr. Mark HymanGrade C
- Gary BreckaGrade C
- Peter Diamandisnot graded
- Siim LandGrade C
Compounds & supplements
- CreatineGrade B+
- Omega-3 (EPA & DHA)not graded
- Vitamin Dnot graded
- Magnesiumnot graded
- Taurinenot graded
- NMN — dosage & verdictGrade C
- Collagen peptidesnot graded
- Peptides — evidence mapnot graded
- BPC-157not graded
- GHK-Cu (copper peptide)not graded
- GLP-1 drugsnot graded
- MetforminGrade D
- RapamycinGrade D
Interventions
- Caloric restrictionGrade B
- Intermittent fastingGrade B
- SenolyticsGrade D
Hubs & resources
- Protocol comparison — experts side by sidenot graded
- Clinical trials — active longevity researchnot graded
- Longevity YouTube channels we monitornot graded
How to read the grades. A–D is the strength of the human evidence for the protocol as a whole: A = consistent randomised trials in people, B = solid but limited human data, C = mixed or mostly observational, D = animal or mechanistic data only. “Not graded” means an overall grade has not been assigned yet — the page still grades its individual claims.
Nothing here is medical advice. Talk to your doctor before starting or stopping anything, especially prescription drugs such as metformin, rapamycin or GLP-1 agonists.