Dr. Karan: 92% Drop in Suicidal Thoughts From Hormones?

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Peer-Reviewed Research
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Dr. Karan

Video Summary · April 16, 2026

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Key Takeaways

  • Hormone therapy shows 92% reduction in suicidal thoughts in women taking all three key hormones
  • Clinics tracking symptom improvement see statistically significant benefits between first and second appointments
  • Suicide risk peaks in late 40s – hormone imbalances may be a major contributing factor
  • Hormone therapy outperforms antidepressants/antipsychotics for symptom relief in this population

Notable Quotes

“92% reduction in suicide thoughts in women who take all three hormones… I can’t find a study with antidepressants and antipsychotics that has that improvement.”

Bottom Line

Women experiencing suicidal thoughts or mood disturbances in perimenopause/menopause should prioritize comprehensive hormone testing and consider bioidentical hormone replacement therapy before defaulting to psychiatric medications.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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