Dr. Karan: Why 30% of Depression Patients Don’t Respond to Antidepressants

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Peer-Reviewed Research
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Dr. Karan

Video Summary · March 26, 2026

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Key Takeaways

  • Seek alternative treatments if you fall into the 30% with treatment-resistant depression, as standard antidepressants may not be effective.
  • Stay informed about emerging therapies and research, as psychiatry has not significantly advanced treatments for depression in the last 50 years.
  • Prioritize mental health check-ups, especially post-COVID, as mental health disorders have been on the rise globally.

Bottom Line

Explore alternative mental health treatments if traditional antidepressants are ineffective, and stay updated on new developments in psychiatric care.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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