Siim Land: The Surprising Effect of Melatonin Nobody Knows About

ByLongevity Notes Editorial
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Peer-Reviewed Research
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Siim Land

Video Summary · March 5, 2026

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Key Takeaways

  • Melatonin pre-workout can boost growth hormone by 157% (5mg dose) or 106% (0.5mg dose) within 40 minutes.
  • Timing matters: Take melatonin 40-60 minutes before resistance training for peak growth hormone response.
  • Effects persist during exercise: Growth hormone levels remained elevated (~130% above baseline) post-workout.

Supplements & Protocols Mentioned

  • Melatonin: 0.5mg or 5mg doses taken pre-workout (study used 60 minutes before exercise).

Bottom Line

Try 0.5-5mg melatonin 40-60 minutes before resistance training to enhance growth hormone release and recovery. Start with lower doses to assess tolerance.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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