Top 25 Longevity & Healthspan YouTube Channels (2026)
Ranked by subscriber count. Covering English-speaking and global influencers who discuss aging science, supplement protocols, and healthspan optimization.
Last updated: March 2026 · Subscriber counts approximate from public sources · 10 have protocol pages on this site
| # | Channel | Subscribers | Country | Focus | Protocol |
|---|---|---|---|---|---|
| 1 | Andrew Huberman Huberman Lab |
6.5M+ | US | Neuroscience, protocols, supplements | View |
| 2 | Dr. Sten Ekberg Dr. Sten Ekberg |
5.3M+ | US/SE | Keto, fasting, holistic health | — |
| 3 | Thomas DeLauer Thomas DeLauer |
4.0M+ | US | Fasting, keto, supplements, body composition | — |
| 4 | Dr. Mark Hyman Mark Hyman, MD |
1.5M+ | US | Functional medicine, Young Forever | View |
| 5 | Bryan Johnson Bryan Johnson |
1.2M+ | US | Blueprint protocol, anti-aging data | View |
| 6 | Rhonda Patrick FoundMyFitness |
900K+ | US | Biomarker-driven micronutrients, sauna | View |
| 7 | Gary Brecka Gary Brecka |
800K+ | US | MTHFR, biohacking, methylation | View |
| 8 | David Sinclair Lifespan |
500K+ | US/AU | Aging biology, NAD+, epigenetics | View |
| 9 | Peter Attia Peter Attia MD |
500K+ | US | Medicine 3.0, exercise science | View |
| 10 | Dr. Hiroki Shinkai | 500K+ | BR 🇧🇷 | Longevity (Portuguese), nutrition, aging | — |
| 11 | Siim Land | 350K+ | EE 🇪🇪 | Biohacking, fasting, longevity protocols | — |
| 12 | Peter Diamandis | 300K+ | US | Longevity tech, XPRIZE, healthspan | View |
| 13 | Dr. Brad Stanfield | 240K+ | NZ 🇳🇿 | Evidence-based supplement reviews | View |
| 14 | Dr. Gabrielle Lyon | 200K+ | US | Muscle-centric medicine, protein | — |
| 15 | Max Lugavere | 200K+ | US | Brain food, Genius Foods, cognitive health | — |
| 16 | Marcos Apud | 200K+ | ES/LATAM 🇪🇸 | Biohacking (Spanish), neuroscience | — |
| 17 | Matt Kaeberlein Optispan |
150K+ | US | Aging science, rapamycin, skeptical voice | View |
| 18 | Dr. Andy Galpin | 150K+ | US | Exercise physiology, performance | — |
| 19 | Physionic | 130K+ | US | Evidence-based study breakdowns | — |
| 20 | Modern Healthspan | 100K+ | US | Supplement protocol updates | — |
| 21 | Felix Harder | 80K+ | DE 🇩🇪 | Science-based nutrition | — |
| 22 | Sheekey Science Show | 70K+ | UK 🇬🇧 | Aging research deep dives | — |
| 23 | Jesse Chappus | 60K+ | CA 🇨🇦 | Health interviews | — |
| 24 | Conquer Aging or Die Trying | 50K+ | US | Aging science community | — |
| 25 | Louisa Nicola Neuro Athletics |
50K+ | AU/US | Neuroathletics, peak performance | — |
Methodology & notes
Subscriber counts are approximate, compiled from public YouTube data, Feedspot, and Favikon rankings (March 2026). This list focuses on channels where longevity, healthspan, or aging science is a primary topic — not general health or fitness channels that occasionally discuss longevity. “Protocol” column links to our detailed protocol pages for influencers who publicly share their supplement stacks. Global channels are flagged with country emoji. This ranking will be updated when we integrate the YouTube Data API for live subscriber tracking.