Matt Kaeberlein: Reacts to Round 2 of Longevity March Madness (Live Results Reveal)

Key Takeaways

• Not smoking beats sleep optimization (65.5% vs 34.5%) – prioritize quitting smoking first
• Strength training outperforms nutrition (62% vs 38%) – lift weights before obsessing over perfect diets
• Blood pressure control crushes PCSK9 inhibitors (88% vs 12%) – monitor and manage BP as foundation
• Rapamycin dominates Urolithin A (79% vs 21%) – focus on proven longevity drugs first
• Sauna use edges out HRV tracking (54% vs 46%) – implement heat therapy before biohacking metrics

Supplements & Protocols Mentioned

• Astaxanthin vs Glycine (Glycine won 65% vs 35%)
• TRIIIM Protocol (growth hormone for thymus regeneration) lost to Acarbose 60% vs 40%
• Omega-3 optimization beat environmental toxin avoidance 62% vs 38%

Notable Quotes

“I think having friends is probably more important to overall health span than healthy body composition… but healthy body composition won with 58% of the vote”

Bottom Line

Focus on foundational health interventions (smoking cessation, strength training, blood pressure control) before experimental supplements or biohacks. Vote in the next round at longevitynotes.org to shape the longevity priority list.

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