Siim Land: If I Had to Take Only 5 Supplements, These Would Be It

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Peer-Reviewed Research
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Siim Land

Video Summary · February 23, 2026

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Key Takeaways

  • Take Astaxanthin (2-12 mg/day) for skin UV protection, eye health, and improved biomarkers like cholesterol and inflammation.
  • Supplement Omega-3s daily to maintain an omega-3 index above 8% for cardiovascular, brain, and metabolic health.
  • Use Glycine (5-10 grams/day) to support collagen synthesis, sleep, and liver health, as dietary intake is often insufficient.
  • Incorporate NAC occasionally to boost glutathione, enhance exercise performance, and improve mitochondrial function.
  • Take Niacinamide (200 mg/day) as a cost-effective NAD booster with skin-protective and anti-aging benefits.

Supplements & Protocols Mentioned

  • Astaxanthin: 2-12 mg/day for skin, eye health, and inflammation reduction.
  • Omega-3s: Daily supplement to maintain omega-3 index above 8%.
  • Glycine: 5-10 grams/day for collagen synthesis, sleep, and liver health.
  • NAC: Occasional use for glutathione synthesis and exercise enhancement.
  • Niacinamide: 200 mg/day as an NAD booster and skin protector.
  • Vitamin D: Supplement if deficient, paired with Vitamin K2 to reduce calcification risk.
  • Magnesium: Beneficial when supplementing vitamin D for calcium balance.

Notable Quotes

“Astaxanthin is amazing, and I have no intentions to stop taking it.”

“Glycine induces autophagy, lowers inflammation, mimics methionine restriction, and has other systemic health benefits.”

Bottom Line

Focus on these five core supplements—Astaxanthin, Omega-3s, Glycine, NAC, and Niacinamide—for measurable health benefits, and consider Vitamin D, K2, and Magnesium if deficient.

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Medical Disclaimer

This article is for informational purposes only and does not constitute medical advice. The research summaries presented here are based on published studies and should not be used as a substitute for professional medical consultation. Always consult a qualified healthcare provider before making any changes to your health regimen.

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